ncRNA name | Malat1 |
ncRNA Category | lncRNA |
ID | NA |
Ensembl | NA |
Synonyms | NA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | transfection, qRT-PCR, ELISA, luciferase reporter assay, immunoprecipitation |
Expression pattern | up-regulated |
Functional description | MALAT1-miR-124-MCP-1 signaling pathway may be involved in AGA-induced MCP-1 expression in microglial cells, which may provide a new approach for the treatment of DR. |
PubMed ID | 30151700 |
Year | 2018 |
Title | Long noncoding RNA MALAT1 acts as a competing endogenous RNA to regulate Amadori-glycated albumin-induced MCP-1 expression in retinal microglia by a microRNA-124-dependent mechanism. |
Drug-related ncRNA | NO |
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